The Penguins did not say when Murray was injured, but Canadiens forward Brendan Gallagher collided with him in the first period Saturday, apparently shaking up the goalie.
Penguins coach Mike Sullivan is expected to give an update on Murray’s status after Tuesday’s practice.
Murray, 24, has been plagued by injuries during his career, including a concussion last season. Murray, who has two Stanley Cups on his résumé, was limited to 49 games in each of the past two seasons.
In two games this season, Murray has given up 11 goals on 65 shots for a 5.47 goals-against average and .831 save percentage.