Pedroia’s injury swelled up in the subsequent innings, limiting his range of motion.
Pedroia was the second batter hit by Astros pitcher James Hoyt pitch in the 7th inning, hitting Mookie Betts in the right knee in the previous at-bat. Home plate umpire Greg Gibson issued warnings to both benches after Pedroia glared and yelled at Hoyt. Both managers came onto the field as Pedroia continue to scream and pointed at the mound before calming down and heading to first base.
ESPN’s Scott Lauber and The Associated Press contributed to this report.